Promimic AB |
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Concept Development |
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Project: HANANO Surface |
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The Challenge
The implant industry is driven by a search for improved materials and better implant surfaces in order to improve clinical results and develop new products. The progress in recent years has led to the development of several new implant materials; such as PEEK, Zirconia and Pyrocarbon. These materials have mechanical properties that make them similar to bone, but do not have the same ability to integrate with the bone as traditional titanium implants. By coating these materials with the Promimic HAnano Surface, an implant is created with mechanical properties and chemistry almost identical to bone.
Promimic's Solution
Promimic is a biomaterials company that develops and markets a unique implant coating – HAnano Surface™. The 20 nm thin coating of hydroxyapatite, HA, accelerates osseointegration and increases the anchoring strength of implants. The HAnano Surface can convert any implant to a material that resembles human bone and thereby create an improved osteoconductive interface between human tissue and implant.
Competitive Advantages
HAnano Surface can be applied on all implant materials, including metals, ceramics, pyrocarbon and polymers - regardless of its dimensions and structure. Compared to competing micrometer thick alternatives HAnano Surface is nanometer thin, which preserve the micro-structure of the implant and reduce the risk of cracks in the coating. Furthermore, the nano thin coating improves the hydrophilicity of the implant material which increases the possibility for bone cells to attach to the surface. The surface has been evaluated both in vitro and in vivo studies, which have shown that the surface can reduce healing times by half.
The Market
The implant industry is a high growth business with high profit margins. The competition amongst implant manufacturers is fierce and each market segment is dominated by four to eight global companies. Many of these follow a strategy of licensing new technology in order to strengthen their product portfolio and market position. This has created an opportunity for innovations from small companies to enter the market. To take advantage of this Promimic has a business model where its technology is out-licensed to implant manufacturers and incorporated into their line of production.
Status
- HAnano Surface has received FDA approval for a dental implant
- First patient study is being finalized
- Collaboration discussions are ongoing with several leading implant companies
Planned Milestones
- Initiate a second study in patients
- Launch of an implant with HAnano Surface
- Expand the product portfolio with a synthetic bone formula
Patent Status
Patent for the company's primary innovation has been granted in Sweden, USA, Russia, China, Israel, Australia, and South Africa and is currently patent pending on all other major markets worldwide. The company is also proactively strengthening its patent portfolio with new applications.
Commercialization
Through collaborations and licensing, Promimic aims to become the implant industry's preferred supplier of synthetic bone interfaces between implant and human tissue.
The HAnano Surface has successfully been sold on the biosensor market since 2007.
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| Contact: Ulf Brogren, CEO | +46 31 772 80 22 | info@promimic.se | www.promimic.se |